|
DATE11/05/2025
|
SYMBOLNONE
|
NAMESilver Point Capital L.P.
|
POSITION10 percent owner
|
ACTIONDISPOSED 0 SHARES
|
|
DATE11/10/2025
|
SYMBOLAORT
|
NAMEMackin James P
|
POSITIONofficer: President & CEO
|
ACTIONDISPOSED 17580 SHARES
|
|
DATE11/07/2025
|
SYMBOLIII
|
NAMECONNORS MICHAEL P
|
POSITIONdirector, 10 percent owner, officer: CHAIRMAN & CEO
|
ACTIONDISPOSED 248935 SHARES
|
|
DATE11/10/2025
|
SYMBOLIII
|
NAMECONNORS MICHAEL P
|
POSITIONdirector, 10 percent owner, officer: CHAIRMAN & CEO
|
ACTIONDISPOSED 78476 SHARES
|
|
DATE11/11/2025
|
SYMBOLIII
|
NAMECONNORS MICHAEL P
|
POSITIONdirector, 10 percent owner, officer: CHAIRMAN & CEO
|
ACTIONDISPOSED 100096 SHARES
|
|
DATE11/12/2025
|
SYMBOLIII
|
NAMECONNORS MICHAEL P
|
POSITIONdirector, 10 percent owner, officer: CHAIRMAN & CEO
|
ACTIONDISPOSED 66196 SHARES
|
|
DATE11/10/2025
|
SYMBOLAORT
|
NAMEDavis John E
|
POSITIONofficer: Chief Commercial Officer
|
ACTIONDISPOSED 3373 SHARES
|
|
DATE11/10/2025
|
SYMBOLAORT
|
NAMEHorton Amy
|
POSITIONofficer: VP, Chief Accounting Officer
|
ACTIONDISPOSED 1789 SHARES
|
|
DATE11/10/2025
|
SYMBOLAORT
|
NAMEStanton Marshall S.
|
POSITIONofficer: SVP, Clinical & MD Affair
|
ACTIONDISPOSED 2566 SHARES
|
|
DATE11/10/2025
|
SYMBOLHIMS
|
NAMEBoughton Soleil
|
POSITIONofficer: Chief Legal Officer
|
ACTIONDISPOSED 2637 SHARES
|
|
DATE11/11/2025
|
SYMBOLOUST
|
NAMETewksbury Ted L III
|
POSITIONdirector
|
ACTIONDISPOSED 1695 SHARES
|
|
DATE11/12/2025
|
SYMBOLHIMS
|
NAMEDudum Andrew
|
POSITIONdirector, 10 percent owner, officer: Chief Executive Officer
|
ACTIONACQUIRED 1954379 SHARES
|
|
DATE11/10/2025
|
SYMBOLHIMS
|
NAMEDudum Andrew
|
POSITIONdirector, 10 percent owner, officer: Chief Executive Officer
|
ACTIONACQUIRED 1049692 SHARES
|
|
DATE11/07/2025
|
SYMBOLHIMS
|
NAMEDudum Andrew
|
POSITIONdirector, 10 percent owner, officer: Chief Executive Officer
|
ACTIONACQUIRED 262423 SHARES
|
|
DATE11/10/2025
|
SYMBOLHIMS
|
NAMEDudum Andrew
|
POSITIONdirector, 10 percent owner, officer: Chief Executive Officer
|
ACTIONDISPOSED 260000 SHARES
|
|
DATE11/12/2025
|
SYMBOLHIMS
|
NAMEDudum Andrew
|
POSITIONdirector, 10 percent owner, officer: Chief Executive Officer
|
ACTIONDISPOSED 1954379 SHARES
|
|
DATE11/07/2025
|
SYMBOLRHLD
|
NAMEMahoney Timothy O.
|
POSITIONdirector
|
ACTIONACQUIRED 397 SHARES
|
|
DATE11/07/2025
|
SYMBOLRHLD
|
NAMEMahoney Timothy O.
|
POSITIONdirector
|
ACTIONACQUIRED 1512 SHARES
|
|
DATE11/07/2025
|
SYMBOLRHLD
|
NAMEMahoney Timothy O.
|
POSITIONdirector
|
ACTIONACQUIRED 2234 SHARES
|
|
DATE11/07/2025
|
SYMBOLRHLD
|
NAMEMahoney Timothy O.
|
POSITIONdirector
|
ACTIONACQUIRED 876 SHARES
|
|
DATE11/07/2025
|
SYMBOLRHLD
|
NAMEMahoney Timothy O.
|
POSITIONdirector
|
ACTIONACQUIRED 364 SHARES
|
|
DATE11/07/2025
|
SYMBOLRHLD
|
NAMEMahoney Timothy O.
|
POSITIONdirector
|
ACTIONACQUIRED 91 SHARES
|
|
DATE11/07/2025
|
SYMBOLRHLD
|
NAMEMahoney Timothy O.
|
POSITIONdirector
|
ACTIONACQUIRED 115 SHARES
|
|
DATE11/07/2025
|
SYMBOLRHLD
|
NAMEMahoney Timothy O.
|
POSITIONdirector
|
ACTIONACQUIRED 350 SHARES
|
|
DATE11/07/2025
|
SYMBOLRHLD
|
NAMESchoen Kurt
|
POSITIONofficer: Chief Financial Officer
|
ACTIONACQUIRED 1000 SHARES
|
|
DATE11/10/2025
|
SYMBOLNONE
|
NAMEWelch Stephen Andrew
|
POSITIONofficer: EVP & Head of Spec Generics
|
ACTIONACQUIRED 43771 SHARES
|
|
DATE11/11/2025
|
SYMBOLNBHC
|
NAMESpring Maria F
|
POSITIONdirector
|
ACTIONDISPOSED 6214 SHARES
|
|
DATE11/11/2025
|
SYMBOLMNKD
|
NAMEAhuja Ajay
|
POSITIONofficer: Chief Medical Officer
|
ACTIONACQUIRED 318200 SHARES
|
|
DATE11/07/2025
|
SYMBOLXPOF
|
NAMEVoss Capital, LP
|
POSITION10 percent owner
|
ACTIONDISPOSED 0 SHARES
|
|
DATE11/07/2025
|
SYMBOLXPOF
|
NAMEVoss Capital, LP
|
POSITION10 percent owner
|
ACTIONDISPOSED 0 SHARES
|
|
DATE11/10/2025
|
SYMBOLKVYO
|
NAMEHallen Ed
|
POSITIONdirector, 10 percent owner:
|
ACTIONDISPOSED 50920 SHARES
|
|
DATE11/10/2025
|
SYMBOLKVYO
|
NAMEHallen Ed
|
POSITIONdirector, 10 percent owner:
|
ACTIONDISPOSED 40512 SHARES
|
|
DATE11/11/2025
|
SYMBOLKVYO
|
NAMEHallen Ed
|
POSITIONdirector, 10 percent owner:
|
ACTIONDISPOSED 2266 SHARES
|
|
DATE11/10/2025
|
SYMBOLKVYO
|
NAMEHallen Ed
|
POSITIONdirector, 10 percent owner:
|
ACTIONDISPOSED 8572 SHARES
|
|
DATE11/11/2025
|
SYMBOLKVYO
|
NAMEHallen Ed
|
POSITIONdirector, 10 percent owner:
|
ACTIONDISPOSED 545 SHARES
|
|
DATE11/07/2025
|
SYMBOLHOWL
|
NAMEEVNIN LUKE
|
POSITIONdirector
|
ACTIONDISPOSED 43950 SHARES
|
|
DATE11/10/2025
|
SYMBOLHOWL
|
NAMEEVNIN LUKE
|
POSITIONdirector
|
ACTIONDISPOSED 31172 SHARES
|
|
DATE11/11/2025
|
SYMBOLHOWL
|
NAMEEVNIN LUKE
|
POSITIONdirector
|
ACTIONDISPOSED 35818 SHARES
|
|
DATE11/12/2025
|
SYMBOLHOWL
|
NAMEEVNIN LUKE
|
POSITIONdirector
|
ACTIONDISPOSED 26101 SHARES
|
|
DATE10/31/2025
|
SYMBOLIDAI
|
NAMELong Lake Capital Management, LLC
|
POSITION10 percent owner:
|
ACTIONDISPOSED 0 SHARES
|
|
DATE11/12/2025
|
SYMBOLLAB
|
NAMECasdin Partners Master Fund, L.P.
|
POSITIONdirector, 10 percent owner:
|
ACTIONACQUIRED 375000 SHARES
|
|
DATE11/11/2025
|
SYMBOLLAB
|
NAMECasdin Partners Master Fund, L.P.
|
POSITIONdirector, 10 percent owner:
|
ACTIONACQUIRED 300000 SHARES
|
|
DATE11/10/2025
|
SYMBOLLAB
|
NAMECasdin Partners Master Fund, L.P.
|
POSITIONdirector, 10 percent owner:
|
ACTIONACQUIRED 275000 SHARES
|
|
DATE11/07/2025
|
SYMBOLLAB
|
NAMECasdin Partners Master Fund, L.P.
|
POSITIONdirector, 10 percent owner:
|
ACTIONACQUIRED 225000 SHARES
|
|
DATE11/11/2025
|
SYMBOLAMGN
|
NAMEREESE DAVID M
|
POSITIONofficer: EVP & Chief Technology Officer
|
ACTIONDISPOSED 6490 SHARES
|
|
DATE11/12/2025
|
SYMBOLAMGN
|
NAMEREESE DAVID M
|
POSITIONofficer: EVP & Chief Technology Officer
|
ACTIONDISPOSED 309 SHARES
|
|
DATE11/07/2025
|
SYMBOLBRBR
|
NAMESINGH ROBIN
|
POSITIONofficer: CHIEF SUPPLY CHAIN OFFCR PNC
|
ACTIONDISPOSED 221 SHARES
|
|
DATE11/11/2025
|
SYMBOLBRBR
|
NAMESINGH ROBIN
|
POSITIONofficer: CHIEF SUPPLY CHAIN OFFCR PNC
|
ACTIONDISPOSED 1806 SHARES
|
|
DATE11/07/2025
|
SYMBOLBRBR
|
NAMECORNILLE DOUGLAS J
|
POSITIONofficer: CHIEF GROWTH OFFICER PNC
|
ACTIONDISPOSED 335 SHARES
|
|
DATE11/07/2025
|
SYMBOLBRBR
|
NAMEDAVENPORT DARCY HORN
|
POSITIONofficer: PRES. AND CEO
|
ACTIONDISPOSED 2280 SHARES
|
|
DATE11/07/2025
|
SYMBOLBRBR
|
NAMEROSENTHAL CRAIG L
|
POSITIONofficer: CLO & SECRETARY
|
ACTIONDISPOSED 267 SHARES
|
|
DATE11/07/2025
|
SYMBOLBRBR
|
NAMERODE PAUL A
|
POSITIONofficer: CFO & TREASURER
|
ACTIONDISPOSED 308 SHARES
|
|
DATE11/07/2025
|
SYMBOLPI
|
NAMESYLEBRA CAPITAL LLC
|
POSITIONother: See Footnotes
|
ACTIONDISPOSED 6246 SHARES
|
|
DATE11/10/2025
|
SYMBOLHAS
|
NAMECochran Hope F
|
POSITIONdirector
|
ACTIONDISPOSED 4000 SHARES
|
|
DATE11/07/2025
|
SYMBOLAMGN
|
NAMEISHRAK OMAR
|
POSITIONdirector
|
ACTIONACQUIRED 218 SHARES
|
|
DATE11/07/2025
|
SYMBOLHOWL
|
NAMEMPM BioVentures 2014, L.P.
|
POSITION10 percent owner
|
ACTIONDISPOSED 68480 SHARES
|
|
DATE11/10/2025
|
SYMBOLHOWL
|
NAMEMPM BioVentures 2014, L.P.
|
POSITION10 percent owner
|
ACTIONDISPOSED 48570 SHARES
|
|
DATE11/11/2025
|
SYMBOLHOWL
|
NAMEMPM BioVentures 2014, L.P.
|
POSITION10 percent owner
|
ACTIONDISPOSED 55810 SHARES
|
|
DATE11/12/2025
|
SYMBOLHOWL
|
NAMEMPM BioVentures 2014, L.P.
|
POSITION10 percent owner
|
ACTIONDISPOSED 40669 SHARES
|
|
DATE11/10/2025
|
SYMBOLPEN
|
NAMERoberts Johanna
|
POSITIONofficer: EVP, Gen. Counsel & Secretary
|
ACTIONDISPOSED 11 SHARES
|
|
DATE11/10/2025
|
SYMBOLPEN
|
NAMERoberts Johanna
|
POSITIONofficer: EVP, Gen. Counsel & Secretary
|
ACTIONDISPOSED 13 SHARES
|
|
DATE11/10/2025
|
SYMBOLPEN
|
NAMERoberts Johanna
|
POSITIONofficer: EVP, Gen. Counsel & Secretary
|
ACTIONDISPOSED 168 SHARES
|
|
DATE11/10/2025
|
SYMBOLPEN
|
NAMERoberts Johanna
|
POSITIONofficer: EVP, Gen. Counsel & Secretary
|
ACTIONDISPOSED 211 SHARES
|
|
DATE11/10/2025
|
SYMBOLPEN
|
NAMERoberts Johanna
|
POSITIONofficer: EVP, Gen. Counsel & Secretary
|
ACTIONDISPOSED 85 SHARES
|
|
DATE11/10/2025
|
SYMBOLPEN
|
NAMERoberts Johanna
|
POSITIONofficer: EVP, Gen. Counsel & Secretary
|
ACTIONDISPOSED 76 SHARES
|
|
DATE11/10/2025
|
SYMBOLPEN
|
NAMERoberts Johanna
|
POSITIONofficer: EVP, Gen. Counsel & Secretary
|
ACTIONDISPOSED 36 SHARES
|
|
DATE11/07/2025
|
SYMBOLAMGN
|
NAMEHOLLEY CHARLES M
|
POSITIONdirector
|
ACTIONACQUIRED 265 SHARES
|
|
DATE11/07/2025
|
SYMBOLHOWL
|
NAMEGADICKE ANSBERT
|
POSITION10 percent owner
|
ACTIONDISPOSED 68480 SHARES
|
|
DATE11/10/2025
|
SYMBOLHOWL
|
NAMEGADICKE ANSBERT
|
POSITION10 percent owner
|
ACTIONDISPOSED 48570 SHARES
|
|
DATE11/11/2025
|
SYMBOLHOWL
|
NAMEGADICKE ANSBERT
|
POSITION10 percent owner
|
ACTIONDISPOSED 55810 SHARES
|
|
DATE11/12/2025
|
SYMBOLHOWL
|
NAMEGADICKE ANSBERT
|
POSITION10 percent owner
|
ACTIONDISPOSED 40669 SHARES
|
|
DATE11/10/2025
|
SYMBOLAPPF
|
NAMEBarat Elizabeth Erin
|
POSITIONofficer: Chief People Officer
|
ACTIONDISPOSED 269 SHARES
|
|
DATE11/10/2025
|
SYMBOLAPPF
|
NAMEBarat Elizabeth Erin
|
POSITIONofficer: Chief People Officer
|
ACTIONDISPOSED 183 SHARES
|
|
DATE11/10/2025
|
SYMBOLAPPF
|
NAMEBarat Elizabeth Erin
|
POSITIONofficer: Chief People Officer
|
ACTIONDISPOSED 146 SHARES
|
|
DATE11/10/2025
|
SYMBOLAPPF
|
NAMEBarat Elizabeth Erin
|
POSITIONofficer: Chief People Officer
|
ACTIONDISPOSED 110 SHARES
|
|
DATE11/10/2025
|
SYMBOLAPPF
|
NAMEBarat Elizabeth Erin
|
POSITIONofficer: Chief People Officer
|
ACTIONDISPOSED 88 SHARES
|
|
DATE11/10/2025
|
SYMBOLAPPF
|
NAMEBarat Elizabeth Erin
|
POSITIONofficer: Chief People Officer
|
ACTIONDISPOSED 86 SHARES
|
|
DATE11/10/2025
|
SYMBOLAPPF
|
NAMEBarat Elizabeth Erin
|
POSITIONofficer: Chief People Officer
|
ACTIONDISPOSED 45 SHARES
|
|
DATE11/10/2025
|
SYMBOLAPPF
|
NAMEBarat Elizabeth Erin
|
POSITIONofficer: Chief People Officer
|
ACTIONDISPOSED 101 SHARES
|
|
DATE11/07/2025
|
SYMBOLAMGN
|
NAMEDrake Michael V
|
POSITIONdirector
|
ACTIONACQUIRED 218 SHARES
|
|
DATE11/10/2025
|
SYMBOLAPPF
|
NAMEEaton Timothy Mathias
|
POSITIONofficer: Chief Financial Officer
|
ACTIONDISPOSED 27 SHARES
|
|
DATE11/10/2025
|
SYMBOLAPPF
|
NAMEEaton Timothy Mathias
|
POSITIONofficer: Chief Financial Officer
|
ACTIONDISPOSED 31 SHARES
|
|
DATE11/10/2025
|
SYMBOLAPPF
|
NAMEEaton Timothy Mathias
|
POSITIONofficer: Chief Financial Officer
|
ACTIONDISPOSED 35 SHARES
|
|
DATE11/10/2025
|
SYMBOLAPPF
|
NAMEEaton Timothy Mathias
|
POSITIONofficer: Chief Financial Officer
|
ACTIONDISPOSED 75 SHARES
|
|
DATE11/10/2025
|
SYMBOLAPPF
|
NAMEEaton Timothy Mathias
|
POSITIONofficer: Chief Financial Officer
|
ACTIONDISPOSED 70 SHARES
|
|
DATE11/10/2025
|
SYMBOLAPPF
|
NAMEEaton Timothy Mathias
|
POSITIONofficer: Chief Financial Officer
|
ACTIONDISPOSED 124 SHARES
|
|
DATE11/10/2025
|
SYMBOLAPPF
|
NAMEEaton Timothy Mathias
|
POSITIONofficer: Chief Financial Officer
|
ACTIONDISPOSED 159 SHARES
|
|
DATE11/10/2025
|
SYMBOLADPT
|
NAMEROBINS HARLAN S
|
POSITIONofficer: Chief Scientific Officer
|
ACTIONDISPOSED 10000 SHARES
|
|
DATE11/10/2025
|
SYMBOLPCOR
|
NAMEFleming William Fred Jr
|
POSITIONofficer: SVP, Corporate Controller
|
ACTIONACQUIRED 2311 SHARES
|
|
DATE11/10/2025
|
SYMBOLPCOR
|
NAMEFleming William Fred Jr
|
POSITIONofficer: SVP, Corporate Controller
|
ACTIONDISPOSED 22000 SHARES
|
|
DATE11/10/2025
|
SYMBOLPCOR
|
NAMEFleming William Fred Jr
|
POSITIONofficer: SVP, Corporate Controller
|
ACTIONDISPOSED 2311 SHARES
|
|
DATE11/11/2025
|
SYMBOLPCOR
|
NAMEBueker Kathryn
|
POSITIONdirector
|
ACTIONDISPOSED 6500 SHARES
|
|
DATE11/10/2025
|
SYMBOLAPPF
|
NAMETrigg William Shane
|
POSITIONdirector, officer: Chief Executive Officer
|
ACTIONDISPOSED 538 SHARES
|
|
DATE11/10/2025
|
SYMBOLAPPF
|
NAMETrigg William Shane
|
POSITIONdirector, officer: Chief Executive Officer
|
ACTIONDISPOSED 1709 SHARES
|
|
DATE11/10/2025
|
SYMBOLAPPF
|
NAMETrigg William Shane
|
POSITIONdirector, officer: Chief Executive Officer
|
ACTIONDISPOSED 219 SHARES
|
|
DATE11/10/2025
|
SYMBOLAPPF
|
NAMETrigg William Shane
|
POSITIONdirector, officer: Chief Executive Officer
|
ACTIONDISPOSED 795 SHARES
|
|
DATE11/10/2025
|
SYMBOLAPPF
|
NAMETrigg William Shane
|
POSITIONdirector, officer: Chief Executive Officer
|
ACTIONDISPOSED 377 SHARES
|
|
DATE11/10/2025
|
SYMBOLAPPF
|
NAMETrigg William Shane
|
POSITIONdirector, officer: Chief Executive Officer
|
ACTIONDISPOSED 238 SHARES
|
|
DATE11/10/2025
|
SYMBOLAPPF
|
NAMETrigg William Shane
|
POSITIONdirector, officer: Chief Executive Officer
|
ACTIONDISPOSED 203 SHARES
|
|
DATE11/11/2025
|
SYMBOLATI
|
NAMEHarris Timothy J
|
POSITIONofficer: Senior VP and CDIO
|
ACTIONDISPOSED 10543 SHARES
|
